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This cascade results in the cleavage of Gasdermin D, leading to the formation of membrane pores that may contribute to cell lysis and the release of the proinflammatory cytokines interleukin (IL)-1 and IL-18

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As a result, we are proposing that the maximum new technology add-on payment for a case involving the use of the Phagenyx System would be $3,250 for FY 2024 (that is, 65 percent of the average cost of the technology)

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